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Calcium D-glucarate is a botanical extract found in grapefruit, apples, oranges, broccoli, spinach, and Brussels sprouts. It is also made naturally in small quantities by the body.
Diindolylmethane (DIM) is formed in the body from plant substances contained in “cruciferous” vegetables such as cabbage, Brussels sprouts, cauliflower, and broccoli.
What are the benefits?
High levels of beta-glucuronide increase the number of oestrogen receptors. This means oestrogen that would have been excreted is now able to bind to more receptors. This can cause increased weight gain (especially around the abdomen), cancer, and even man boobs.
Oestrogen dominance is one of the leading causes of infertility, cancer, and other health problems in women.
In one study, calcium-d-glucarate was able to reduce the number of oestrogen receptors by 48 percent. It’s also been shown to lower serum oestrogen levels by 23 percent. High oestrogen is also a problem for men. Whether you are a man or woman, calcium-d- glucarate can help towards maintaining proper hormone balance.
The exact mechanism of action of DIM is unknown, but doctors Michael Zeligs and Scott Connelly state in their book, “All About DIM,” that some of the benefits are likely derived from the fact that DIM helps to balance the sex hormones oestrogen and testosterone. They explain that when oestrogen is broken down in your body, it can either form beneficial or harmful oestrogen metabolites, and DIM helps your body to break down oestrogen into the beneficial type.
The beneficial oestrogen metabolites have antioxidant properties and help to protect the heart and brain from free-radical damage. Diindolylmethane also simultaneously reduces the levels of harmful oestrogen metabolites, which is beneficial because they are associated with an increased risk for obesity, breast cancer and uterine cancer. Additional problems associated with too many harmful oestrogen metabolites include moodiness and breast pain in women and loss of sex drive in men.
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